Plasma histamine concentration during propranolol induced bronchoconstriction.
نویسندگان
چکیده
منابع مشابه
Pulmonary gas exchange during histamine-induced bronchoconstriction in asthmatic subjects.
Bronchial provocation for testing airway hyperreactivity is now well-established. However, the effects of histamine-induced bronchoconstriction on pulmonary gas exchange in man have not been systematically studied. We empirically noted marked decreases in PaO2 in some asthmatic subjects following induced bronchoconstriction. Nine subjects with mild, stable asthma were studied, each on two separ...
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BACKGROUND Inhaled propranolol causes bronchoconstriction in asthmatic subjects by an indirect mechanism which remains unclear. Inhaled frusemide has been shown to attenuate a number of indirectly acting bronchoconstrictor challenges. The aim of this study was to investigate whether frusemide could protect against propranolol-induced bronchoconstriction in patients with stable mild asthma. ME...
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PURPOSE Midazolam has been used clinically as a sedative and as an anaesthetic induction agent. However, the bronchodilating effects of midazolam have not been comprehensively evaluated. We sought to determine relaxant effects of midazolam on the airway. METHODS After our Animal Care Committee approved the study, eight mongrel dogs were anaesthetized with 30 mg.kg-1 pentobarbitone iv, and wer...
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The review by Gordon 1 concerning a positive correlation between plasma renin substrate concentration (PRS) and blood pressure (BP) prompted us to evaluate our PRS data from a randomized double-blind study on the antihypertensive effect of enalapril (MK 421) compared to propranolol. Twenty-two patients with essential hypertension were treated in subsequent 4-week periods by placebo and 40, 80, ...
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Plasma levels of adrenaline and noradrenaline during and after submaximal exercise in patients with bronchial asthma were investigated. Three groups were studied comprising 10 patients with exercise-induced bronchoconstriction (EIB), 10 asthmatic patients without EIB and four normal control subjects. Plasma catecholamines were measured at rest, at the end of exercise, and five and 15 minutes af...
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ژورنال
عنوان ژورنال: Thorax
سال: 1985
ISSN: 0040-6376
DOI: 10.1136/thx.40.12.903